In Indianapolis, the Panthers kept finding ways to win behind running back Stephen Davis and its all pro defense. Davis had 76 yards rushing before getting pulled out of the game with an injured forearm and being replaced by second year player Deshawn Foster, who had 86 yards on the ground.
The Colts could not come up with a second straight come-from-behind victory, although they did their best to achieve one. Peyton Manning hit Reggie Wayne to tie the game at 20 before going into overtime. That was the last Colt possession, as the Panthers kept handing the ball to Foster and watching him run over the Colt defense. Panther kicker John Kasey hit a 47 yard field goal to win the game.